Ovarian Cancer

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Wake-Up Drug Could Help Sleep-Deprived

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  8/26/2005 8:20 pm
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TUESDAY, Aug. 23 (HealthDay News) -- Shiftworkers, hospital staff clocking long hours, and other sleep-challenged Americans may someday have a means of restoring full alertness even if sleep-deprived.

Researchers at Wake Forest University in Winston-Salem, N.C., say an experimental drug called CX717 temporarily improved performance and reversed the effects of sleep deprivation in the brains of monkeys.

The drug works on a type of brain receptor involved in cell-to-cell communication, boosting the action of the neurotransmitter glutamate.

Reporting late Monday in the online edition of the Public Library of Science-Biology, the team first taught alert, well-rested monkeys to pick out specific images from a range of others flashed on a computer screen. Use of CX717 improved test scores of these fully alert monkeys to near-perfect, the researchers report.

Learn more at:

http://health.ivillage.com/brain/0,,wbnews_84bn02xf,00.html?ice=iv|wb|news,alert

IVHealth Ruth Ann
Community Leader/Ask the Health Librarian

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