I've been noticing that after I edit my RAW files in ACR, play with them in CS4 and then save them as jpegs, the noise is out of control! It's SO much more than when I used to just shoot in jpeg. I am also using CS4 now instead of CS3 so I suppose maybe that could have something to do with it as well (maybe a setting?). I took a bunch of photos with iso 800 and the noise looks like it was at least 1600, if not 32000.
What do you think is going on?