I don't know what colic calm is, but gripe water has various natural things in it that are supposed to soothe reflux & gas (for example: dill oil, fennel oil). Online, you can check the ingredients of various kinds. It didn't work for my colicky baby, but I hope it helps yours. If anything, it won't harm your baby and might be worth a try! Keep in mind that this phase will pass. I understand how hard it is! Best wishes, Jen