Just as an FYI--
My medium-sized law firm has made our last 4 staff hires through Craiglist. We had much better responses than from the newspaper and the postings on Craiglist are free. Paper resumes, unless handed over during an interview, are pretty much a thing of the past.
Updated skills are crucial to re-entering the work force. I know I hire people who will make my life easier, not people I have to hand hold through every task. A big part of this is excellent computer skills on commonly used office software.
Also, if someone is coming back after a year or more of staying at home (and notes this on the resume or tells me this in the interview), I would expect some reassurances that he/she has adequate and reliable childcare so that he/she can be reliable. This is not something an employer may legally ask about, but it may benefit the applicant to mention that childcare is a non-issue and that regular and punctual attendance will be a priority to the applicant.
Don't forget that the normal rules of resumes apply--no typos, easy to read, explains what you have done and how you will benefit the company. . .